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简介：Landresourcesarefacingcrisesofbeingmisused,especiallyforanintersectionareabetweentownandcountry,andlandcontrolhastobeenforced.Thispaperpresentsadevelopmentofdataminingmethodforlandcontrol.Avector-matchmethodfortheprerequisiteofdataminingi.e.,datacleaningisproposed,whichdealswithbothcharacterandnumericdataviavectorizingcharacter-stringandmatchingnumber.Aminimaldecisionalgorithmofroughsetisusedtodiscovertheknowledgehiddeninthedatawarehouse.Inordertomonitorlandusedynamicallyandaccurately,itissuggestedtosetupareal-timelandcontrolsystembasedonGPS,digitalphotogrammetryandonlinedatamining.Finally,themeansisappliedintheintersectionareabetweentownandcountryofWuhancity,andasetofknowledgeaboutlandcontrolisdiscovered.

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简介：TheapplicationsofbionicmethodologydevelopedbytheLaboratoryofDesignandMaterialSelectionasbasisinthecreationofjunctionelementsweredemonstrated.TheseelementsfavortheapplicationofEcodesigninreferencetotheeffec-tivenessofproductdismountaimingthereductionofambientimpactinallitsphasesofuse.Thecreation,thedevelopmentandtheconfectionofnewjunctionelementsweredescribed,andcasestudiesofnewproductsdevelopedspecificallywiththispurposewerepresented.

简介：WesternChinahaslaggedalotintermsofindustrialstructureandeconomicdevelopment,comparedwiththenationalaverage.AndChinaannounceditstargetofCO2emissionreduction,i.e.by2020,CO2emissionperGDPwilldropby40-45%comparedwith2005.ThetargetwillbeincorporatedintoChina’slong-termindustrialplanning.Againstthisbackground,thispaperwillmakeacomprehensiveexaminationoftheindustrialdevelopmentofWesternChina,aimingtodiscoveragreenandcompatibleway.First,weanalyzethespatiotemporalevolutionofregionalindustrialstructurefortheperiod2000-2010.Second,wetrytodiscovertheindustrialstructureoptimizationpathforWesternChinabyemployingtheVectorAutoRegressionmodel.Lastly,wetrytoprovidesomeadviceandsuggestionsforfurtherindustrialdevelopmentinWesternChina.OurexaminationshowsthatfurtherindustrialdevelopmentinWesternChinashouldpayfullattentiontoresourceconservationandrecycling,anddeveloponagreenandcompatiblepath.

简介：ApoptosisplaysanessentialroleinTcellbiology.ThymocytesexpressingnonfunctionalorautoreactiveTCRsareeliminatedbyapoptosisduringdevelopment.ApoptosisalsoleadstothedeletionofexpandedeffectorTcellsduringimmuneresponses.Thedysregulationofapoptosisintheimmunesystemresultsinautoimmunity,tumorogenesisandimmunodeficiency.Twomajorpathwaysleadtoapoptosis:theintrinsiccelldeathpathwaycontrolledbyBcl-2familymembersandtheextrinsiccelldeathpathwaycontrolledbydeathreceptorsignaling.Thesetwopathwaysworktogethertoregu

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简介：AbstractCilia are microtubule-based filamentous organelles that play a vital role in embryogenesis. Multiple signal transduction pathways are orchestrated by cilia, such as Hedgehog and planar cell polarity signals. Various studies, spanning over last 2 decades, have emphasized the role of cilia-mediated signaling cascades in regulating neural tube patterning anddevelopment. Moreover, the deficiency of certain ciliary genes have been reported to cause neural tube defects (NTDs), which are a set of disorders that occur due to perturbation of normal neural tube closure. However, the mechanisms underlying cilia dysfunction resulting NTDs remain unclear. Recent studies have highlighted the association of phosphoinositide signaling with cilia, thereby conferring novel insights into the function of cilia during neural tubedevelopment. Here, we have reviewed recent studies on cilia, focusing on the molecular mechanism underlying the involvement of cilia in neural tubedevelopmentand the role of ciliary disruption in thedevelopmentof NTDs.

简介：AbstractServing as the interface between the fetal and maternal environments during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of maternal health. The placenta is primarily derived from the embryonic trophectoderm which differentiates into various subtypes of trophoblast cells through villous and extravillous pathways. The interactions among trophoblasts and multiple decidual cells and immune cells at the maternal-fetal interface fundamentally form the functional units of the placenta, which are responsible for blood perfusion and maternal-fetal material exchange, immune tolerance, and the regulation of pregnancy adaptation. Defects in placentaldevelopmentand functional maintenance are in tight association with adverse pregnancy outcomes such as preeclampsia. In this article, we review recent advances on human trophoblast cell differentiation and the construction of placental functional units and discuss the placental and maternal factors that may contribute to the occurrence of preeclampsia.

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简介： <正> Brazil,asagreatdevelopingcountry,signedtheagreementonandbecameoneofthethirty-oneoriginalsignatorycountriesofGATTmorethanthirtyyearsago.WhatbenefithasBrazilobtainedfromthepreferenceofferedtodevelopingcountriesbyGATT?WhateffectonearthdidGATTtakeontheeconomyofBrazil?First,let’shaveareviewonthedevelop-

简介：TheadventoftheInternetconsumptionerahaspromotedthedevelopmentofproductionmode,lifemodeandthinkingmode,leadingtothe'newnormal'ofinnovation-drivendevelopmentandcausingthechangeofalltradesandprofessions.Moreover,thetourismindustryisalsoaffectedgreatlybyit,whichbroughtanewdevelopmentopportunityfortraditionaltourism.Underthebackgroundofthisera,asaprovinceoftourismresources,thetourismindustryofHubeiProvinceshouldunderstandtheadvantagesanddisadvantagesofitsdevelopment,andseekthecorrespondingsolutionsaccordingtothetimes’background,inordertoseektherapiddevelopmentof'Internet+tourism'andpromotethesustainabledevelopmentofeconomy.

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简介：TheBohai,thelargestinlandseainChina,isabundantinmarineresources.However,withthepapereconomicgrowthintheCricum-BohaiBayAreaintherecentyears,theenvironmentalpollutioninthisareahasbecomemoreandmoreserious,resultinginasubstantialdeclineanddeteriorationofmarineresources.Inviewofthiscriticalsituation,themethodforsustainabledevelopmentofmarineresourcesintheBohaiSeaisdiscussed.Practicalmeasuresandfeasiblesuggestionsareputforwardinthispaperwiththepurposeofpreventingandcontrollingenvironmentalpollutionaswellasnaturaldisasters,andeventuallyachievingtheaimofthesustainabledevelopmentofmarineresourcesinthisarea.

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