Left ventricular regional and global diastolic function assessed using Quantitative Tissue velocity Imaging in patients with hypertrophic cardiomyopathy-中国Betway体育网页登陆

摘要 ObjectivesThestudywasperformedtoassesstheleftventricular(LV)regionalandglobaldiastolicfunction,leftventricularwallmotionfeaturesinpatientswithHypertrophiccardiomyopathybyQuantitativeTissueVelocityImaging(QTVI).Methods42patientswithhypertrophiccardiomyopathyand36age-matchednormalsubjectsunderwentQTVIstudy.Off-lineLVregionalmusculartissuevelocityImagingalongLVapicallong-axisviewwereobtained.RegionaldiastolicfunctionwasassessedinusingpeaktissuevelocitiesofLVregionalmusculartissueduringearlydiastole(Ve)andLAcontraction(Va),Ve/Varatio,derivedfromTissueVelocityImaging.Globaldiastolicfunctionwasreflectedbyisovolumicrelaxationtime(IRT)andmitralvalvepeakflowvelocity(E/A)calculatedwithpulsedwavedoppler.Theend-diastolicinterventricularseptalthickness(IVSt)wasmeasuredbyconventional2-dimensionechocardiography.Results①Ve,Va,Ve/Vainthesegmentsofhypertrophicinterventricularseptum(IVS)reducedwlhileE/AratiosignificantlyreducedandIRTmarkedlyprolongedinHCMpatientsthaninnormalsubjects.②Ve,Ve/VaweresignificantreducedinthesegmentsofhypertrophicinterventricularseptumcomparedwithotherLVsegmentsinHCMpatients.③TherewasacorrelationbetweenVe/VaandE/AinHCMpatientswithabnormalE/Aratio(r=0.70).④TherewasanegativecorrelationbetweenVe/VaandIVStinnon-obstructionHCMpatients(Bgroup,r=-0.61)ConclusionsQTVIoffersanewermethodinclinicalpracticewhichhasahighersensibilityandaccuracyinevaluatingtheLVregionalandglobaldiastolicfunctioninHCMpatients.

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Left ventricular regional and global diastolic function assessed using Quantitative Tissue velocity Imaging in patients with hypertrophic cardiomyopathy

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