摘要
Objective:Toexploretheroleofthetexturefeaturesofimagesinthediagnosisofsolitarypulmonarynodules(SPNs)indifferentsizes.Materialsandmethods:Atotalof379patientswithpathologicallyconfirmedSPNswereenrolledinthisstudy.TheyweredividedintothreegroupsbasedontheSPNsizes:≤10,11-20,and>20mm.Theirtexturefeaturesweresegmentedandextracted.ThedifferencesintheimagefeaturesbetweenbenignandmalignantSPNswerecompared.TheSPNsinthesethreegroupsweredeterminedandanalyzedwiththetexturefeaturesofimages.Results:These379SPNsweresuccessfullysegmentedusingthe2DOtsuthresholdmethodandtheself-adaptivethresholdsegmentationmethod.ThetexturefeaturesoftheseSPNswereobtainedusingthemethodofgreylevelco-occurrencematrix(GLCM).Ofthese379patients,120hadbenignSPNsand259hadmalignantSPNs.Theentropy,contrast,energy,homogeneity,andcorrelationwere3.5597±0.6470,0.5384±0.2561,0.1921±0.1256,0.8281±0.0604,and0.8748±0.0740inthebenignSPNsand3.8007±0.6235,0.6088±0.2961,0.1673±0.1070,0.7980±0.0555,and0.8550±0.0869inthemalignantSPNs(allP<0.05).Thesensitivity,specificity,andaccuracyofthetexturefeaturesofimageswere83.3%,90.0%,and86.8%,respectively,forSPNssized≤10mm,andwere86.6%,88.2%,and87.1%,respectively,forSPNssized11-20mmand94.7%,91.8%,and93.9%,respectively,forSPNssized>20mm.Conclusions:Theentropyandcontrastofmalignantpulmonarynoduleshavebeendemonstratedtobehigherincomparisontothoseofbenignpulmonarynodules,whiletheenergy,homogeneitycorrelationofmalignantpulmonarynodulesarelowerthanthoseofbenignpulmonarynodules.Thetexturefeaturesofimagescanreflectthetissuefeaturesandhavehighsensitivity,specificity,andaccuracyindifferentiatingSPNs.ThesensitivityandaccuracyincreaseforlargerSPNs.更多还原
出版日期
2014年04月14日(中国Betway体育网页登陆平台首次上网日期,不代表论文的发表时间)