简介:Thephilosophicalrootofallhumanbeings'existencecrisisinthecontemporarytimesisthephilosophyoftheunfimitedtheory.Theinnerspiritualsupportingforceistheconstructionfromitstheoreticalreasontoitsscientificreason.Itsessentialideasstemfromthepeople-centeredtheory,theviewofhappinessinthematerialpurposedtheory,thecommunistlifestyle,thematerialhegemonistprinciple,andtherationalactionprinciplesofeconomictechnology.Inthe21stcentury,inordertodealwiththedangeroussituationofhumanbeings'existencefromtheroot,thephilosophyofthelimitationtheorymustbeestablished,whichhastheeco-reasonasthevaluesupport,integratesalltheoriginalwisdomofhumanbeingsandreflectshuman'sspiritualneedsoftheageaswellasthedirectionofhumanfuturedevelopment.Thewholeperceptofthisnewphilosophyisthat“allthingshavesouls”;itsbasiclawofexistenceis“theceaselessfifecircle”,itssurvivalgoalistheviewofhappinessintheharmonyofmaterialandspirit;itssocialactionguidanceandprincipleare(environment,society,humanity)theenvironmentecologismandtheintegral-and-mutualactionprinciple(ofhumanbeings&society,individual&society,andpresentage&posterity).
简介:假如你碰到这样的选择题:Thereasonheis late isitrained.A.thatB.because正确答案是哪一个呢?也许这样的题你见得太多了,会说选A。是的,出题者正是这样想的;许许多多的试题也是这样设计的。当然,thereasonis后的表语从句用连词that引导是没有问题的,大量的例句证明了这一点。但是,一些参考书和各种考试指导书一律把这一结构中用because判作错误。有的解释说“because引起的表语从句只能用在it(this,that)isbecause的结构里”,“thereason…that这种结构常常会误用成thereason...because”。有的把用because当成典型错误例析,说“名词reason不能与表示原因的because同用在一个句子里,以免犯重复的错误,例如不能说:Thereasonwhyhedidthejobpoorlyisbecausehelackedenthusiasm.这里应把because改为that”。有的在英文正误句举例说“中文是说‘……的原因是因为……’,但英语绝对不能说thereaso...
简介:ThepaperdiscussesquantitativelytheinfluenceoftheYutianMS7.4earthquakeofMarch21,2008andWuqiaMS6.9earthquakeofOctober5,2008onregionalseismicityinXinjiang,andexplainsprimarilythepossiblereasonofearthquakeactivityfeatureinXinjiangaftertheYutianMS7.4earthquakebyanalyzingthestaticCoulombfailurestresschangeproducedbytheYutianMS7.4earthquakeandWuqiaMS6.9earthquake,andtheseismicityfeatureofMS≥3earthquakesinthepositiveCoulombstresschangeregionofKashi-Wuqiajointregion,thecentralsegmentofTianshanMountainandKalpinblock.TheresultshowsthattheYutianMS7.4earthquakeofMarch21,2008,mayencouragetheWuqiaMS6.9earthquakeofOctober5,2008,andtheYutianMS7.4earthquakeandWuqiaMS6.9earthquakemaychangetheseismicitystateinthecentralsegmentofTianshanMountain,KalpinblockandKashi-Wuqiajointregion,andencouragethesubsequentMS≥3earthquakes.
简介:AIM:Toinvestigatetheeffectsofhydrogen-richsaline(HRS)onmicrogliaactivationandSirtuintype1(Sirt1)inratswithN-methyl-N-nitrosourea(MNU)-inducedretinitispigmentosa(RP).METHODS:Ratsweredividedintonorm(N)group,model(M)groupandHRS(H)group.RatsinMandHgroupsweregivensalineandHRSrespectivelypriortoandafteradministrationofMNU.Atoneday(d1)andd3afterwards,electroretinogramandhistologicalexaminationwereperformedtoconfirmtheeffectsofHRSonretinalfunctionandstructureofMNU-inducedRP.Immunofluorescencestainingofanti-ionizedcalcium-bindingadaptermolecule1(Iba1),amakerofmicrogliacells,wasperformed,withquantitativereal-timepolymerasechainreaction(qRT-PCR)foritsmRNAquantification.Moreover,Sirt1mRNAandproteinexpressionintheretinasweredetectedbyWesternblotandqRT-PCR.RESULTS:HRSpreservedtheretinalfunctionandmitigatedthereductionofphotoreceptordegenerationinMNU-treatedretinas.ThepresenceofmicrogliacellswassomewhatmoreobviousinHgroupthanthatinMgroupatd1.HRSsuppressedthefurtheractivationofmicrogliacells,withthenumberofmicrogliacellslessthanthatofMgroupatd3.ResultsofqRT-PCRofIba1wereconsistentwiththoseofimmunofluorescencestaining,withthemRNAexpressionofIba1inHgroupmoreintensivethanthatofMgroupatd1(P<0.05),whilelessthanthatofMgroupatd3(P<0.05).Furthermore,theSirt1mRNAandproteinexpressiondecreasedafterMNUadministration,whileHRSmitigatedtheMNU-induceddownregulationofSirt1.CONCLUSION:HRScaneffectivelykeepmicrogliaactivationinducedbyMNUtoanappropriateextent,whileupregulateSirt1inMNU-inducedRP.