301例肾癌的诊断治疗及预后分析

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    摘要 摘要目的探讨近年中国人肾癌的发病特点,提高肾癌的诊治水平。方法回顾性分析2009至2013年收治的301例肾癌患者,通过分析患者的年龄分布、临床表现特点、影像学与实验室检查结果,治疗及预后随访情况,探讨肾癌的诊治现状。结果301例患者发病年龄16~85岁,平均54岁。病程2天~20年,平均7月。其中有临床症状者105例(34.9%),表现为血尿29例(9.6%),腰部酸痛58例(19.3%),腰腹部肿块者4例(1.3%)。诊断以B超、CT为主。本组全部病例均行B超检查,发现占位性病变者299例(99.3%);行CT检查者228例(75.7%),均发现占位性病变。行根治性肾切除术治疗者247例(82.1%),采用保留肾单位手术治疗者54例(17.9%)。透明细胞癌242例(80.4%),乳头状肾细胞癌9例(3.0%),肾嫌色细胞癌26例(8.6%),其他类型24例(包括囊性肾细胞癌、集合管癌、肉瘤样癌和混合性肾细胞癌等)。随访时间1~51个月,平均30个月,期间有17例死亡,1例复发,8例转移。总的5年生存率达91.5%。根据2010年AJCC肾癌TNM分期,其中I期肾癌的5年特异性生存率为97.0%,II期肾癌为84.2%。结论只要早期及时发现,并根据临床分期选择适当的手术治疗方式,就能极大的改善肾癌的生存预后情况。
    出处 《医药界》 2014年10期
    关键词 肾肿瘤 诊断 治疗DiagnosisandtreatmentofrenalcellcarcinomaFuGuanghou,JinBaiye(TheFirstAffiliatedHospital,CollegeofMedicine,ZhejiangUniversity,Hangzhou,Zhejiang310003)AbstractObjectiveToresearchtheclinicalmanifestationsofrenalcellcarcinomaofChineseinrecentyears,andimprovethediagnosisandtreatmentofrenalcellcarcinoma(RCC).MethodsClinicaldataof301RCCcasesfrom2009to2013wereretrospectivelyanalyzed.Analyzedtheagedistribution,clinicalmanifestationcharacter,resultoficonographyandlaboratoryexamination,treatmentandprognosis.ResultsThemeanageofoverall301patientswithRCCwas54years(range16~85years).Thecourseofthisdiseasewasfrom2daysto20years(mean7months).Amongthe301patients,105(34.9%)caseshadclinicalsymptoms,includinghematuria(9.6%),lumbodynia(19.3%)andabdominalmass(1.3%).ThediagnosticmeansweremainlyultrasonographyandCTscanning.ThepositivediagnosticrateofRCCwas99.3% inType-BUltrasonic(301cases),100.0% inCTtest(228cases).Radicalnephrectomywasdonefor247(82.1%)andpartialnephrectomyfor54(17.9%).Thepathologic
    出版日期 2014年10月20日(中国Betway体育网页登陆平台首次上网日期,不代表论文的发表时间)
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    医药界

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    肾肿瘤 诊断 治疗DiagnosisandtreatmentofrenalcellcarcinomaFuGuanghou,JinBaiye(TheFirstAffiliatedHospital,CollegeofMedicine,ZhejiangUniversity,Hangzhou,Zhejiang310003)AbstractObjectiveToresearchtheclinicalmanifestationsofrenalcellcarcinomaofChineseinrecentyears,andimprovethediagnosisandtreatmentofrenalcellcarcinoma(RCC).MethodsClinicaldataof301RCCcasesfrom2009to2013wereretrospectivelyanalyzed.Analyzedtheagedistribution,clinicalmanifestationcharacter,resultoficonographyandlaboratoryexamination,treatmentandprognosis.ResultsThemeanageofoverall301patientswithRCCwas54years(range16~85years).Thecourseofthisdiseasewasfrom2daysto20years(mean7months).Amongthe301patients,105(34.9%)caseshadclinicalsymptoms,includinghematuria(9.6%),lumbodynia(19.3%)andabdominalmass(1.3%).ThediagnosticmeansweremainlyultrasonographyandCTscanning.ThepositivediagnosticrateofRCCwas99.3% inType-BUltrasonic(301cases),100.0% inCTtest(228cases).Radicalnephrectomywasdonefor247(82.1%)andpartialnephrectomyfor54(17.9%).Thepathologic
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