Exercise-induced rhabdomyolysis mechanisms and prevention:A literature review

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    摘要 Exercise-inducedrhabdomyolysis(exRML),apathophysiologicalconditionofskeletalmusclecelldamagethatmaycauseacuterenalfailureandinsomecasesdeath.IncreasedCa2+levelincellsalongwithfunctionaldegradationofcellsignalingsystemandcellmatrixhavebeensuggestedasthemajorpathologicalmechanismsassociatedwithexRML.TheonsetofexRMLmaybeexhibitedinathletesaswellasingeneralpopulation.PreviousstudieshavereportedthatpossiblecausesofexRMLwereassociatedwithexcessiveeccentriccontractionsinhightemperature,abnormalelectrolytesbalance,andnutritionaldeficienciespossiblegeneticdefects.However,theunderlyingmechanismsofexRMLhavenotbeenclearlyestablishedamonghealthprofessionalsorsportsmedicinepersonnel.Therefore,wereviewedthepossiblemechanismsandcorrelatedpreventionofexRML,whileprovidingusefulandpracticalinformationfortheathleteandgeneralexercisingpopulation.
    机构地区 不详
    出版日期 2016年03月13日(中国Betway体育网页登陆平台首次上网日期,不代表论文的发表时间)
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