Cochlear implants in genetic deafness-中国Betway体育网页登陆

摘要 Geneticdefectsareoneofthemostimportantetiologiesofseveretoprofoundsensorineuralhearinglossandplayanimportantroleindeterminingcochlearimplantationoutcomes.Whilethepathogenicmutationtypesofanumberofdeafnessgeneshavebeencloned,thepathogenesismechanismsandtheirrelationshiptotheoutcomesofcochlearimplantationremainahotresearcharea.Theauditoryperformanceisconsideredtobeaffectedbytheetiologyofhearinglossandthenumberofsurvivingspiralganglioncells,aswellasothers.Currentresearchadvancesincochlearimplantationforhereditarydeafness,especiallytherelationshipamongclinic-types,genotypesandoutcomesofcochlearimplantation,willbediscussedinthisreview.

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Cochlear implants in genetic deafness

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