Clinical features of AIDS patients with Hodgkin＇s lymphoma with isolated bone marrow involvement： report of 12 cases at a single institution-中国Betway体育网页登陆

摘要 Objective:Tostudythemainclinicalandhistopathologicalfeaturesof12patientswithHodgkin'slymphoma(HL)diagnosedprimarilyfrombonemarrow(BM)involvement.Methods:Weincluded12acquiredimmunodeficiencysyndrome(AIDS)patientswithHLassistedintheF.J.Mu?izInfectiousDiseasesHospitalsinceJanuary2002toDecember2013.ThediagnosisofHLwithprimaryBMinvolvementinpatientswasconfirmedbyclinical,histopathological,andimmunohistochemicalfindings.Results:Allpatientspresented'B'symptomsandpancytopenia.AllofthemhadstageIVneoplasmdiseasebecauseofBMinfiltration.ThemedianofCD4+T-cellcountswas114cells/μL,andmixedcellularity(MC)wasthemostfrequenthistopathologicalsubtypeof92%cases.Conclusion:Whenothercausesareexcluded,BMbiopsyshouldbeperformedinAIDSpatientswith'B'symptomsandpancytopeniatoevaluateBMinfiltrationbyatypicallymphocytes.

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Clinical features of AIDS patients with Hodgkin＇s lymphoma with isolated bone marrow involvement： report of 12 cases at a single institution

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