Research progress on the anticarcinogenic actions and mechanisms of ellagic acid-中国Betway体育网页登陆

摘要 Cancerisaleadingcauseofdeathworldwide.Cancertreatmentsbychemotherapeuticagents,surgery,andradiationhavenotbeenhighlyeffectiveinreducingtheincidenceofcancersandincreasingthesurvivalrateofcancerpatients.Inrecentyears,plant-derivedcompoundshaveattractedconsiderableattentionasalternativecancerremediesforenhancingcancerpreventionandtreatmentbecauseoftheirlowtoxicities,lowcosts,andlowsideeffects.Ellagicacid(EA)isanaturalphenolicconstituent.RecentinvitroandinvivoexperimentshaverevealedthatEAelicitsanticarcinogeniceffectsbyinhibitingtumorcellproliferation,inducingapoptosis,breakingDNAbindingtocarcinogens,blockingvirusinfection,anddisturbinginflammation,angiogenesis,anddrug-resistanceprocessesrequiredfortumorgrowthandmetastasis.ThisreviewenumeratestheanticarcinogenicactionsandmechanismsofEA.ItalsodiscussesfuturedirectionsontheapplicationsofEA.

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Research progress on the anticarcinogenic actions and mechanisms of ellagic acid

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