Craniocerebral injury promotes the repair of peripheral nerve injury

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    摘要 Theincreaseinneurotrophicfactorsaftercraniocerebralinjuryhasbeenshowntopromotefracturehealing.Moreover,neurotrophicfactorsplayakeyroleintheregenerationandrepairofperipheralnerve.However,whethercraniocerebralinjuryalterstherepairofperipheralnerveinjuriesremainspoorlyunderstood.Ratinjurymodelswereestablishedbytransectingtheleftsciaticnerveandusingafree-falldevicetoinducecraniocerebralinjury.Comparedwithsciaticnerveinjuryaloneafter6–12weeks,ratswithcombinedsciaticandcraniocerebralinjuriesshoweddecreasedsciaticfunctionalindex,increasedrecoveryofgastrocnemiusmusclewetweight,recoveryofsciaticnervegangliaandcorrespondingspinalcordsegmentneuronmorphologies,andincreasednumbersofhorseradishperoxidase-labeledcells.Theseresultsindicatethatcraniocerebralinjurypromotestherepairofperipheralnerveinjury.
    机构地区 不详
    出版日期 2014年12月22日(中国Betway体育网页登陆平台首次上网日期,不代表论文的发表时间)
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