Comprehensive treatment of a functional pancreatic neuroendocrine tumor with multifocal liver metastases-中国Betway体育网页登陆

摘要 A64-year-oldmanwasadmittedtotheSunYat-SenUniversityCancerCenterwithchiefcomplaintsofrecurrentabdominalpainanddiarrheaforabout3yearsandwithahistoryofsurgicalrepairforintestinalperforationowingtostressulcer.Positronemissiontomography(PET)/computedtomography(CT)demonstratedaprimarytumoronthepancreatictailwithmultifocallivermetastases.Pathologicalandimmunohistochemistrystainingrevealedthelesiontobeapancreaticneuroendocrinetumor(pNET).AccordingtothelatestWorldHealthOrganization(WHO,2013)classification,thetumorwasclassifiedasstageIVfunctionalG1pNET.Afterreferraltothemultidisciplinarytreatmentboard(MDT),thepatientwasstartedonperiodicdoseofomeprazole,somatostatinanaloguesandInterferonα(IFNα)andhadscanningfollow-ups.Basedupontheimagingresults,CT-guidedradioactiveiodine-125(125I)seedsimplantationtherapy,radiofrequencyablationtherapy(RFA)ormicrowaveablationtechniquewerechosenforthetreatmentoftheprimarytumor.Transarterialchemoembolization(TACE),RFAandmicrowaveablationtechniquesweredecideduponforlivermetastases.Thepatientshowedbeneficialresponsetothetreatmentwithclinicallymanageablelow-gradesideeffectsandattainedpartialremission(RECISTcriteria)withagoodqualityoflife.

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Comprehensive treatment of a functional pancreatic neuroendocrine tumor with multifocal liver metastases

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