In vivo photoacoustic chorioretinal vascular imaging in albino mouse-中国Betway体育网页登陆

摘要 Photoacousticophthalmoscopy(PAOM)isanovelimagingmodality,whichiscapableofnon-invasivelydetectingopticalabsorptionpropertiesintheretina.WevisualizethemicrovasculatureinretinaandchoroidinalbinomouseusingPAOMguidedbyspectral-domainopticalcoherencetomography.Sincealbinomousecharacterizesbylackingmelanininretinalpigmentepithelium(RPE),PAOMilluminationlasercanpenetratethroughtheRPEontochoroid,andconsequentlyprovidesvolumetricvisualizationofchorioretinalvasculaturesasaresultofstronghemoglobinopticalabsorption.Thehigh-qualitychorioretinalmicrovascularimagingacquiredbyPAOMimpliesitsgreatpotentialinunderstandingpathologicalmechanismsanddevelopingtherapeuticstrategiesformajorchorioretinaldiseasesthatcorrelatewithvasculardisorders.

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In vivo photoacoustic chorioretinal vascular imaging in albino mouse

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