Joint Modeling of Failure Time Data with Transformation Model and Longitudinal Data When Covariates are Measured with Errors-中国Betway体育网页登陆

摘要 Semiparametrictransformationmodelsprovideaclassofflexiblemodelsforregressionanalysisoffailuretimedata.Severalauthorshavediscussedthemunderdifferentsituationswhencovariatesaretimeindependent(Chenetal.,2002;Chengetal.,1995;Fineetal.,1998).Inthispaper,weconsiderfittingthesemodelstoright-censoreddatawhencovariatesaretime-dependentlongitudinalvariablesand,furthermore,maysuffermeasurementerrors.Forestimation,weinvestigatethemaximumlikelihoodapproach,andanEMalgorithmisdeveloped.Simulationresultsshowthattheproposedmethodisappropriateforpracticalapplication,andanillustrativeexampleisprovided.

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Joint Modeling of Failure Time Data with Transformation Model and Longitudinal Data When Covariates are Measured with Errors

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